Former One Life to Live favorite Nathan Fillion celebrates the 100th episode of his primetime hit Castle tonight, with an episode that gives a nod to Alfred Hitchcock's Rear Window.

The Hollywood Reporter caught up with creator Andrew Marlowe, Fillion and his co-star Stana Katic. The trio talked about the show's origins, the impact of the Writers' Strike and reaching the 100-episode milestone. Here's an excerpt:

THR: What's the secret to Castle's success?

Katic: It appeals to an audience that wants dessert after dinner. It's charming in a classic kind of way. I think people love a bit of heart, humor, drama and stakes, so I suppose it has a nice mix of a lot of different emotions.

Fillion: There are episodes where we do go pretty dramatic, but by and large, we don't take ourselves terribly seriously. We keep it fairly light. I think it makes it easy to like.

Marlowe: People have been responding to this love story between Castle and Beckett, and they are hungry for shows that make them laugh. Whatever bit of magic we happen to capture, hopefully we'll be able to continue. The chances of a pilot getting on air are slim, and to reach 100 episodes is a miracle. That's a result of a lot of people's hard work and also a lot of luck. It is harder and harder for TV shows to reach this milestone in an environment where you have Internet streaming, places like Netflix for shows, 100 channels of programs, cable. It just really gratifies us that we happened to find such a wonderful and loyal audience.

Watch the promo for Castle's "The Lives of Others" after the jump!

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Former The Bold and The Beautiful and All My Children star William deVry has landed a guest starring role on ABC’s Castle, just in time for the show’s 100 episode tonight. According to CBS Soaps In Depth, deVry will play multi-millionaire Dan Renner, who becomes a suspect in a murder investigation involving an IRS agent.

Castle airs Mondays at 10 pm EST on ABC.

 

Programs starring daytime suds alums helped ABC win the Monday night ratings race. On the strength of the Season 16 premiere of Dancing With the Stars (featuring General Hospital's Ingo Rademacher) and an episode of Nathan Fillion starrer Castle, ABC bested original lineups on rival networks. READ MORE

General Hospital’s Nancy Lee Grahn and GH alum Jack Wagner, who also played her nephew on Santa Barbara, are set to appear in an upcoming episode of ABC’s Castle, according to TVLine.

Meanwhile, at work, Beckett and her team get caught in the middle of a War of the Roses-esque squabble starring General Hospital‘s Nancy Lee Grahn and Big Love alum Brendan Ford, while GH/Melrose Place vet Jack Wagner guests as a pro golfer whose wife turns up dead. READ MORE

It looks likes Days of Our Lives favorite Charles Shaughnessy will be keeping busy after his return visit to the NBC soap next week. According to TV Guide, Shaughnessy will appear in the Castle episode “The Limey” as Nigel Winthrop, Deputy General to the British Consulate. Castle (Nathan Fillion) and Becket (Stana Katic) will suspect his character of being up to no good.